Progress towards this goal has been hindered by many intrinsic materials problems, such as weak-links, flux-creep, and poor mechanical properties. Three methods were invented to produce flexible metallic substrates, which were also crystallographically biaxially textured, and resembled a long, mosaic single crystal.
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The third method invented is calle Full Text Available Direct sequencing of total plant DNA using next generation sequencing technologies generates a whole chloroplast genome sequence that has the potential to provide a barcode for use in plant and food identification. Advances in DNA sequencing platforms may make this an attractive approach for routine plant identification.
The HiSeq Illumina and Ion Torrent Life Technology sequencing platforms were used to sequence total DNA from rice to identify polymorphisms in the whole chloroplast genome sequence of a wild rice plant relative to cultivated rice cv. Consensus chloroplast sequences were produced by mapping sequence reads to the reference rice chloroplast genome or by de novo assembly and mapping of the resulting contigs to the reference sequence.
A total of polymorphisms SNPs and indels between the wild and cultivated rice chloroplasts were predicted by these different sequencing and analysis methods. Of these, a total of polymorphisms including 90 SNPs were predicted by both platforms. Indels were more variable with different sequencing methods, with almost all discrepancies found in homopolymers. The methods should be suitable for routine barcoding using appropriate combinations of sequencing platform and data analysis. Additionally, we got an average sequence depth for the genome of for the Iontorrent PGM and for the FLX platform making the mapping suitable for single nucleotide variant SNV detection.
Next Generation Sequencing NGS is becoming more adopted into viral research and will be the preferred technology in the years to come. The second generation biofuels from the biomass. The author takes stock on the second generation biofuels in the world, the recent technologies, their advantages, the research programs and the economical and environmental impacts of the biofuels development.
The study indicates that while second generation biofuels could significantly contribute to the future energy supply mix, cost is a major barrier to its commercial production in the near to medium term. Depending upon type of biofuels, feedstock prices and conversion costs, the cost of cellulosic ethanol is found to be two to three times higher than the current price of gasoline on an energy equivalent basis.
The median cost across the studies reviewed of biodiesel produced from microalgae, a prospective feedstock, is seven times higher than the current price of diesel, although much higher cost estimates have been reported. While significant cost reductions are needed for both types of second generation biofuels, the critical barriers are at different steps of the production process.
For cellulosic ethanol, the biomass conversion costs needs to be reduced. On the other hand, feedstock cost is the main issue for biodiesel. At present, policy instruments, such as fiscal incentives and consumption mandates have in general not differentiated between the first and second generation biofuels except in the cases of the US and EU. The policy regime should be revised to account for the relative merits of different types of biofuels.
These new sensors will complement the firstgeneration medium-resolution pushbroom and high-definition video cameras that were mounted on the Russian segment of the ISS in early The Canadarm will then be used to install the remote sensing platform onto a CBM Common Berthing Mechanism hatch on Node 3, allowing the sensor electronics to be accessible from the inside of the station, thus limiting their exposure to the space environment and allowing for future capability upgrades. The UrtheCast second-generation system will be able to take full advantage of the strengths that each of the individual sensors offers, such that the data exploitation capabilities of the combined sensors is significantly greater than from either sensor alone.
This represents a truly novel platform that will lead to significant advances in many other Earth Observation applications such as environmental monitoring, energy and natural resources management, and humanitarian response, with data availability anticipated to begin after commissioning is completed in early The objectives of this activity are: The work plan for this project activity consists of three major tasks: Definition of expected worst-case environments humidity, liquid composition and temperature at waste package outer surfaces as a function of time, and comparison with environments defined in the YMP baseline; Task 2.
Oxidation and corrosion tests of proposed second-generation outer container material; and Task 3. Second Generation waste package thermal analyses. Full funding was not provided for this project activity. A Second Generation Mobile Robot. Insight into biases and sequencing errors for amplicon sequencing with the Illumina MiSeq platform.
The platform is manageable and affordable even for smaller labs. This enables quick turnaround on a broad range of applications such as targeted gene sequencing , metagenomics, small genome sequencing and clinical molecular diagnostics. However, Illumina error profiles are still poorly understood and programs are therefore not designed for the idiosyncrasies of Illumina data. A better knowledge of the error patterns is essential for sequence analysis and vital if we are to draw valid conclusions. Studying true genetic variation in a population sample is fundamental for understanding diseases, evolution and origin.
We tested state-of-the-art library preparation methods for amplicon sequencing and showed that the library preparation method and the choice of primers are the most significant sources of bias and cause distinct error patterns. A " second generation " of ministry leadership. Catholic health care leaders differ from others in the field in that "they are expected to serve as Jesus served, teach as Jesus taught, and lead as Jesus led, in order to heal as Jesus healed.
This first generation was privileged in that it was tutored by and worked alongside women and men religious. Those religious are now mostly gone from the ministry, and that first generation of lay leaders will also be retiring in the not too distant future. Leadership will then pass to a " second generation ," laypeople who have not worked alongside religious.
How is this new generation to learn "to heal as Jesus healed"? In its efforts to fill a position, the system first assembles a preferred-candidate profile, based on 15 competencies, including seven core competencies. CHE then employs a recruitment process based on behavioral event interviewing. All involved stakeholders participate in the interviews.
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A second generation polymerization monomeric reactants PMR polyimdes matrix system PMR 2 was characterized in both neat resin and composite form with two different graphite fiber reinforcements. Three different formulated molecular weight levels of laboratory prepared PMR 2 were examined, in addition to a purchased experimental fully formulated PMR 2 precurser solution.
Isothermal aging of graphite fibers, neat resin samples and composite specimens in air at C were investigated. Humidity exposures at 65 C and 97 percent relative humidity were conducted for both neat resin and composites for eight day periods. Composites were fire tested on a burner rig developed for this program. Results indicate that neat PMR 2 resins exhibit excellent isothermal resistance and that PMR 2 composite properties appear to be influenced by the thermo-oxidative stability of the reinforcing fiber.
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Progress toward Brazilian cesium fountain second generation. The operation of a Cesium fountain primary frequency standard is strongly influenced by the characteristics of two important subsystems. The first is a stable frequency reference and the second is the frequency-transfer system. A stable standard frequency reference is key factor for experiments that require high accuracy and precision. The frequency stability of this reference has a significant impact on the procedures for evaluating certain systematic biases in frequency standards.
This paper presents the second generation of the Brazilian Cesium Fountain Br-CsF through the opto-mechanical assembly and vacuum chamber to trap atoms. We used a squared section glass profile to build the region where the atoms are trapped and colled by magneto-optical technique. The opto-mechanical system was reduced to increase stability and robustness. This newest Atomic Fountain is essential to contribute with time and frequency development in metrology systems. AC application of second generation HTS wire.
It can be engineered with a high degree of flexibility to manufacture practical 2G conductors with architectures and properties tailored for specific applications and operating conditions. For ac applications conductor and coil design can be geared towards low hysteretic losses. For applications which experience high frequency ac fields, the stabilizer needs to be adjusted for low eddy current losses.
For these applications a stainless-steel laminate is used. An example is a Low Pass Filter Inductor which was developed and built in this work. Methodology toward second generation expert systems. So-called First Generation Expert Systems were aimed at capturing the expert's know-how.
Though providing remarkable achievements, this first wave did not give the expected outcome. A new generation is getting out from the laboratories. Instead of remaining at a shallow level of knowledge - that is the unmotivated reasoning processes expressed by an expert when he is forced to tell them - one attempts to re-build this level of knowledge from the first principles which constitute the basis of an expert's knowledge. These systems are called deep knowledge-based, or second generation expert systems.
Discussion in the three first parts rests on two examples: A first generation and a half system for process control in nuclear powers plants, than the system EXTRA for alarm processing in nuclear plants, wherein fonctional knowledge is explicitely represented. We show how deep knowledge can be implemented, and the advantages that can be expected from this methodology. Qualitative Physics is discussed in the next part. Future research developments as well as potential payoffs are mentioned [fr. Medical Ultrasound Imaging is widely used clinically because of its relatively low cost, portability, lack of ionizing radiation, and real-time nature.
However, even with these advantages ultrasound has failed to permeate the broad array of clinical applications where its use could be of value. A prime example of this untapped potential is the routine use of ultrasound to guide intravenous access. In this particular application existing systems lack the required portability, low cost, and ease-of-use required for widespread acceptance. Our team has been working for a number of years to develop an extremely low-cost, pocket-sized, and intuitive ultrasound imaging system that we refer to as the "Sonic Window.
Through a high degree of custom front-end integration combined with multiplexing down to a 2 channel PC based digitizer this system acquired a full set of RF data over a course of transmit events. While initial results were encouraging, this system exhibited limitations resulting from low SNR, relatively coarse array sampling, and relatively slow data acquisition.
We have recently begun assembling a second-generation Sonic Window system. This system uses a element fully sampled array operating at 5. We present initial results from this front-end and present benchmark results from a software beamformer implemented on the Analog Devices BF DSP. We discuss our immediate plans for further. A second-generation supersonic transport. This is of particular importance with respect to support technology such as airport terminals and runways. Based on the above introductory remarks, a possible approach to the design of a second-generation supersonic civil transport is presented here.
The design Mach number for this aircraft is 3. This value was chosen as it represents the limiting Mach number in the absence of active cooling. The ensuing design attempts to deal with the particular problems that are the most demanding, while relying on proven technology where it is adequate. The report clearly does not solve, or even deal with, every aspect of the aircraft design. Rather, a general direction is suggested and supported with initial, approximate calculations. A second generation genetic map for rainbow trout Oncorhynchus mykiss.
Full Text Available Abstract Background Genetic maps characterizing the inheritance patterns of traits and markers have been developed for a wide range of species and used to study questions in biomedicine, agriculture, ecology and evolutionary biology. The status of rainbow trout genetic maps has progressed significantly over the last decade due to interest in this species in aquaculture and sport fisheries, and as a model research organism for studies related to carcinogenesis, toxicology, comparative immunology, disease ecology, physiology and nutrition.
We constructed a second generation genetic map for rainbow trout using microsatellite markers to facilitate the identification of quantitative trait loci for traits affecting aquaculture production efficiency and the extraction of comparative information from the genome sequences of model fish species. Results A genetic map ordering microsatellite loci spanning a sex-averaged distance of Microsatellite markers, representing pairs of loci resulting from an evolutionarily recent whole genome duplication event, identified duplicated regions within the rainbow trout genome.
Microsatellites associated with genes through expressed sequence tags or bacterial artificial chromosomes produced comparative assignments with tetraodon, zebrafish, fugu, and medaka resulting in assignments of homology for loci. Conclusion The second generation NCCCWA genetic map provides an increased microsatellite marker density and quantifies differences in recombination rate between the sexes in outbred populations. It has the potential to integrate with cytogenetic and other physical maps, identifying paralogous regions of the rainbow trout genome arising from the evolutionarily recent genome duplication event, and.
The second generation of biofuels aims at ; La seconde generation de biocarburants vise Research work is intensifying on the second generation of biofuels in order to optimize the processes and to reduce the production costs. Poorly valorized vegetable resources are targeted in order to avoid conflicts with other agricultural processes. Two ways are explored since several years: So far, no method allows to recover oils with a satisfactory energy efficiency but several pilot-plants are under study or already in operation Futurol, BTL biomass-to-liquid..
The advent of DNA sequencing technologies and the various applications that can be performed will have a dramatic effect on medicine and healthcare in the near future. There are several DNA sequencing platforms available on the market for research and clinical use. Based on the medical laboratory scientist or researcher's needs and taking into consideration laboratory space and budget, one can chose which platform will be beneficial to their institution and their patient population.
Although some of the instrument costs seem high, diagnosing a patient quickly and accurately will save hospitals money with fewer hospital stays and targeted treatment based on an individual's genetic make-up. By determining the type of disease an individual has, based on the mutations present or having the ability to prescribe the appropriate antimicrobials based on the knowledge of the organism's resistance patterns, the clinician will be better able to treat and diagnose a patient which ultimately will improve patient outcomes and prognosis.
A platform -independent method for detecting errors in metagenomic sequencing data: It also provides global whole sample error estimates that can be used to identify samples with high or varying levels of sequencing error that may confound downstream analyses, particularly in the case of studies that utilize data from multiple sequencing samples. For shotgun metagenomic data, we believe that DRISEE provides estimates of sequencing error that are more accurate and less constrained by technical limitations than existing methods that rely on reference genomes or the use of scores e.
We present DRISEE as an open-source, platform -independent method to assess sequencing error in shotgun metagenomic data, and utilize it to discover previously uncharacterized error in de novo sequence data from the and Illumina sequencing platforms. A tale of three next generation sequencing platforms: The pace of change in this area is rapid with three major new sequencing platforms having been released in Here we compare the results obtained with those platforms to the performance of the Illumina HiSeq, the current market leader.
In order to compare these platforms , and get sufficient coverage depth to allow meaningful analysis, we have sequenced a set of 4 microbial genomes with mean GC content ranging from Together, these represent a comprehensive range of genome content. Here we report our analysis of that sequence data in terms of coverage distribution, bias, GC distribution, variant detection and accuracy. We analysed the ability to call variants from each platform and found that we could call slightly more variants from Ion Torrent data compared to MiSeq data, but at the expense of a higher false positive rate.
Variant calling from Pacific Biosciences data was possible but higher coverage depth was required. Conclusions All three fast turnaround sequencers evaluated here were able to generate usable sequence. However there are key differences between the quality of that data and the applications it will support. The data generated was largely comparable between sequencing platforms Although we acknowledge our analyses were limited to animal material, our observations suggest that the BGISEQ holds the potential to represent valid and potentially valuable alternative platform for palaeogenomic data generation, that is worthy of future exploration by those interested Use of four next-generation sequencing platforms to determine HIV-1 coreceptor tropism.
In this study, HIV-1 co-receptor usage was predicted for twelve patients scheduled to start a maraviroc-based antiretroviral regimen. Cross- platform variation was evaluated, including number of reads, read length and error rates. Each platform detected all major virus variants within the HIV-1 population with similar frequencies.
Identification of non-R5 viruses was comparable among the four platforms , with minor differences attributable to the algorithms used to infer HIV-1 tropism. In conclusion, all four NGS platforms were able to detect minority non-R5 variants at comparable levels suggesting that any NGS-based method can be used to predict HIV-1 coreceptor usage.
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Europe and the United States. The public debate about the second generation in Europe has taken a dramatic shift in the last five years. The riots in the banlieues in France, involving mostly Algerian and Moroccan second-generation youth, pitched the cherished republican model into deep crisis. In the Netherlands, arguments. A parallel reconfigurable platform for efficient sequence alignment Bioinformatics is one of the emerging trends in today's world. The major part of bioinformatics is dealing with DNA. Analysis of DNA requires more memory and high efficient computations to produce accurate outputs.
Researchers use various bioinformatics algorithms for sequencing and pattern detection techniques, but still Comparison and evaluation of two exome capture kits and sequencing platforms for variant calling. To promote the clinical application of next-generation sequencing , it is important to obtain accurate and consistent variants of target genomic regions at low cost. Ion Proton, the latest updated semiconductor-based sequencing instrument from Life Technologies, is designed to provide investigators with an inexpensive platform for human whole exome sequencing that achieves a rapid turnaround time.
However, few studies have comprehensively compared and evaluated the accuracy of variant calling between Ion Proton and Illumina sequencing platforms such as HiSeq , which is the most popular sequencing platform for the human genome. We then called variants in the exonic regions that overlapped between the two exome capture kits The rates of shared variant loci called by two sequencing platforms were from Sanger sequencing validation revealed that the validated rate of concordant single nucleotide polymorphisms SNPs With regard to 1-bp small insertions and deletions InDels , the Sanger sequencing validated rates of concordant variants In the sequencing of exonic regions, a combination of using of two sequencing strategies SureSelect-HiSeq and TargetSeq-Proton increased the variant calling specificity for concordant variant loci and the sensitivity for variant loci called by any one platform.
Beside the detector, what put the system in the second generation category are the state of the art features implemented in every component. This paper describes the system concept and design consideration have been taken during the development of its components. Next generation sequencing NGS is a powerful tool for the characterization, discovery, and molecular identification of RNA viruses. There were multiple NGS library preparation methods published for strand-specific RNA-seq, but some methods are not suitable for identifying and characterizing RNA viruses.
The NGS sequencing adapters were directly inserted into the sequencing library through reverse transcription and polymerase chain reaction, without fragmentation and ligation of nucleic acids. The results show that this method is simple to perform, able to identify multiple species of RNA viruses in clinical samples. Leptoquarks are hypothetical particles that attempt to explain the coincidental similarities between leptons and quarks included in SM. Their exact properties vary between different theoretical models, and there are no strong theoretical constraints on their possible mass values.
They can possibly be produced from particle collisions, and there have already been searching efforts at previous collider experiments. Their presence have not yet been observed, and this fact has been translated into lower bound exclusions on their possible mass values. The Large Hadron Collider LHC being the most recently constructed particle collider with the highest collision energies ever achieved experimentally, provides a new platform to continue the search for Leptoquarks at even higher mass ranges. This thesis describes a search for pair-produced second-generation Leptoquarks using Events with two oppositely charged muons and two or more jets in the final state were used.
Candidate leptoquark events were selected with the help of four observables: Monte Carlo simulations of SM background processes have shown to be in good agreement with data, both in the region constructed using selection requirements for candidate leptoquark events and in the designated control regions. Since no significant excess of events was observed in data, a exclusion limit was set as a function of the Leptoquark mass. Deep- sequencing protocols influence the results obtained in small-RNA sequencing. Full Text Available Second-generation sequencing is a powerful method for identifying and quantifying small-RNA components of cells.
However, little attention has been paid to the effects of the choice of sequencing platform and library preparation protocol on the results obtained. We present a thorough comparison of small-RNA sequencing libraries generated from the same embryonic stem cell lines, using different sequencing platforms , which represent the three major second-generation sequencing technologies, and protocols.
We have analysed and compared the expression of microRNAs, as well as populations of small RNAs derived from repetitive elements. Despite the fact that different libraries display a good correlation between sequencing platforms , qualitative and quantitative variations in the results were found, depending on the protocol used.
Thus, when comparing libraries from different biological samples, it is strongly recommended to use the same sequencing platform and protocol in order to ensure the biological relevance of the comparisons. Application of human reliability analysis methodology of second generation. The human reliability analysis HRA is a very important part of probabilistic safety analysis. The main contribution of HRA in nuclear power plants is the identification and characterization of the issues that are brought together for an error occurring in the human tasks that occur under normal operation conditions and those made after abnormal event.
Additionally, the analysis of various accidents in history, it was found that the human component has been a contributing factor in the cause. Because of need to understand the forms and probability of human error in the 60 decade begins with the collection of generic data that result in the development of the first generation of HRA methodologies. Subsequently develop methods to include in their models additional performance shaping factors and the interaction between them.
So by the 90 mid, comes what is considered the second generation methodologies. The application of this method in a generic human failure event, it is interesting because it includes in its modeling commission error, the additional deviations quantification to nominal scenario considered in the accident sequence of probabilistic safety analysis and, for this event the dependency actions evaluation.
That is, the generic human failure event was required first independent evaluation of the two related human failure events. So the gathering of the new human error probabilities involves the nominal scenario quantification and cases of significant deviations considered by the potential impact on analyzed human failure events. Like probabilistic safety analysis, with the analysis of the sequences were extracted factors more specific with the highest contribution in the human error probabilities. Recognition of depositional sequences and stacking patterns, Late Devonian Frasnian carbonate platforms , Alberta basin.
Six depositional sequences bounded by regional unconformities or their correlative equivalents sequence boundaries have been recognized in Late Devonian Frasnian carbonate platforms in the Alberta basin. These sequences consist of a predictable vertical succession of smaller scale shoaling-upward cycles parasequences. Parasequences are arranged in retrogradational, aggradational, and progradational stacking patterns that can be modeled as a sediment response to relative changes in sea level.
Sequence boundaries are recognized by onlap onto underlying shelf or shelf margin strata. This onlap includes shelf margin wedges and deep marine onlap. In outcrop sections shelf margin wedges exhibit an abrupt juxtaposition of shallow water facies over deeper water deposits with no gradational facies changes at the boundaries. High on the platform , subaerial exposure fabrics may be present. The shelf margin wedges are interpreted to have formed during lowstands in sea level and typically exhibit an aggradational stacking pattern. On the platform , two types of sequences are recognized.
A type 1 cycle occurs where the sequence boundary is overlain by a flooding surface and subsequent parasequences exhibit retrogradational stacking. In a type 2 cycle the sequence boundary is overlain by an aggradational package of shallow water parasequences, followed by a retrogradational package. These two types of sequences can be modeled using a sinusoidal eustatic sea level curve superimposed on thermo-tectonic subsidence. MiSeq, Illumina's integrated next generation sequencing instrument, uses reversible-terminator sequencing -by-synthesis technology to provide end-to-end sequencing solutions.
The MiSeq instrument is one of the smallest benchtop sequencers that can perform onboard cluster generation, amplification, genomic DNA sequencing , and data analysis, including base calling, alignment and variant calling, in a single run. Thus, MiSeq provides an ideal platform for rapid turnaround time. MiSeq is also a cost-effective tool for various analyses focused on targeted gene sequencing amplicon sequencing and target enrichment , metagenomics, and gene expression studies.
For these reasons, MiSeq has become one of the most widely used next generation sequencing platforms. Here, we provide a protocol to prepare libraries for sequencing using the MiSeq instrument and basic guidelines for analysis of output data from the MiSeq sequencing run. Samples were collected from 6 unrelated individuals by forensic postmortem examination, including chest blood, hair, costicartilage, nail, skeletal muscle and oral epithelium.
Amplification of whole genome sequence of mtDNA was performed by 4 pairs of primer. The whole genome sequence of mtDNA from all samples were amplified successfully. Six unrelated individuals belonged to 6 different haplotypes. Different tissues in one individual had heteroplasmy difference. After a consistency check by the Kappa method, it was found that the results of mtDNA sequence had a high consistency in different tissues. The testing method used in present study for sequencing the whole genome sequence of human mtDNA can detect the heteroplasmy difference in different tissues, which have good consistency.
The results provide guidance for the further applications of mtDNA in forensic science. The development of a diagnostic platform using next generation sequencing. Full Text Available Real-time sequencing of short DNA reads has a wide variety of clinical and research applications including screening for mutations, target sequences and aneuploidy. This novel method shows great promise as a clinical diagnostic test for applications requiring rapid short-read DNA sequencing. Sequencing of BAC pools by different next generation sequencing platforms and strategies.
Full Text Available Abstract Background Next generation sequencing of BACs is a viable option for deciphering the sequence of even large and highly repetitive genomes. Results Sequencing four BACs with both FLX and Titanium technologies revealed similar sequencing accuracy, but showed that the longer Titanium reads produce considerably less misassemblies and gaps.
Conclusion Optimal BAC pool sequencing should be based on the longest available reads, with barcoding essential for a comprehensive assessment of both repetitive and non-repetitive sequence information. When interest is restricted to non-repetitive regions and repeats are masked prior to assembly, barcoding is non-essential. In any case, the assemblies can be improved considerably by scaffolding with non-barcoded BAC pool MPs.
Adult inmates who experienced the incarceration of a parent, known as " second-generation prisoners," experience unique challenges and are at heightened risk for experiencing other adversities throughout the life span. Our study investigated one specific, and previously unexplored, type of adversity--domestic violence--within a sample of incarcerated adults. We examined the relation between generation status first- or second-generation prisoners , childhood exposure to domestic violence, and participation in adult relationship violence prior to incarceration.
Results indicate that prisoners who had been exposed to domestic violence in childhood were more likely to engage in intimate partner violence resulting in inflicted and received injury. Relative to first-generation prisoners, second-generation prisoners reported more childhood domestic violence exposure and were more likely to have been injured by a relationship partner.
However, this relation between second-generation status and injury victimization was mediated by domestic violence exposure. These results support an intergenerational pattern of domestic violence and suggest that second-generation prisoners are a unique population worthy of future investigation and mental health intervention. Jetson Tegra K1 has several advantages, such as the low cost, low power consumption, and high applicability, and it has been applied into several specific applications. Complex system installation and setup are necessary procedures at first.
By , the American empire will have gone the way of so many empires before it. So says iconoclastic and uncannily prescient libertarian financial engineer Jake Shannon. In ENDonomics, Shannon lays out the causes of the impending collapse of the United States as we know it in clear and simple language: Despite the dismal title referring to the dismal science, Shannon contends that there is good reason to be an "Apocaloptimist". Read and share ENDonomics and learn why the end of the American empire may very well lead to the rebirth of the American Republic! Read more Read less.
Thousands of books are eligible, including current and former best sellers. Look for the Kindle MatchBook icon on print and Kindle book detail pages of qualifying books. Print edition must be purchased new and sold by Amazon. Gifting of the Kindle edition at the Kindle MatchBook price is not available. Learn more about Kindle MatchBook. Kindle Cloud Reader Read instantly in your browser. Editorial Reviews About the Author Having vocally predicted the recent credit crisis while the Manager of Oversight for Complex Instruments at Indymac Bank, Jake Shannon also accurately warned of the current deflation we are experiencing in his Anomaly: Revolutionary Knowledge In Everyday Life.
The Hijacking of Liberty in America. Jake Shannon earned his M. He lives in Salt Lake City with his wife and children. Product details File Size: September 12, Sold by: Share your thoughts with other customers. Write a customer review. Showing of 2 reviews. It moves on to examine the responses of both the dispossessed …. From religious tomes to current folk prophesies, recorded history reveals a plethora of narratives predicting or showcasing the end of the world. The incident at Waco, the subway …. Take This Is the End to the next level. There has never been a This Is the End Guide like this.
It contains answers, much more than you can imagine; comprehensive answers and ….
Related ENDonomics: Default, Deflation, Derivatives & the End of the United States As We Know It.
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